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Red Sox 11, Indians 2
| Cleveland | AB | R | H | BI | BB | SO | Avg. |
| Sizemore cf | 3 | 0 | 1 | 1 | 0 | 1 | .222 |
| ACabrera 2b | 4 | 0 | 1 | 0 | 0 | 1 | .241 |
| Hafner dh | 4 | 1 | 1 | 0 | 0 | 2 | .148 |
| VMartinez c | 4 | 0 | 0 | 0 | 0 | 0 | .296 |
| Garko 1b | 4 | 0 | 1 | 1 | 0 | 0 | .292 |
| JhPeralta ss | 4 | 0 | 1 | 0 | 0 | 0 | .259 |
| Lofton lf | 4 | 0 | 1 | 0 | 0 | 0 | .222 |
| Gutierrez rf | 4 | 1 | 2 | 0 | 0 | 0 | .211 |
| Blake 3b | 4 | 0 | 2 | 0 | 0 | 0 | .346 |
| Totals | 35 | 2 | 10 | 2 | 0 | 4 |
| Boston | AB | R | H | BI | BB | SO | Avg. |
| Pedroia 2b | 5 | 3 | 3 | 5 | 0 | 0 | .345 |
| Youkilis 1b | 5 | 2 | 3 | 2 | 0 | 1 | .500 |
| DOrtiz dh | 5 | 0 | 0 | 0 | 0 | 2 | .292 |
| MRamirez lf | 3 | 0 | 1 | 1 | 1 | 1 | .409 |
| Crisp cf | 0 | 0 | 0 | 0 | 0 | 0 | .143 |
| Lowell 3b | 3 | 1 | 2 | 1 | 0 | 1 | .333 |
| JDrew rf | 4 | 1 | 1 | 1 | 0 | 0 | .360 |
| Varitek c | 4 | 2 | 3 | 0 | 0 | 1 | .269 |
| Ellsbury cf-lf | 3 | 2 | 1 | 0 | 1 | 0 | .250 |
| JLugo ss | 3 | 0 | 1 | 0 | 0 | 1 | .200 |
| Totals | 35 | 11 | 15 | 10 | 2 | 7 |
| Cleveland | 000 | 110 | 000—2 | 10 | 1 |
| Boston | 111 | 000 | 26x—11 | 15 | 1 |
E—Blake (1), JLugo (1). LOB—Cleveland 7, Boston 4. 2B—Hafner (1), Garko (2), Pedroia (3), Youkilis (1), Lowell (2), Varitek 2 (3). HR—Youkilis (3), off Lewis; Pedroia (1), off RBetancourt. RBIs—Sizemore (2), Garko (2), Pedroia 5 (5), Youkilis 2 (7), MRamirez (10), Lowell (8), JDrew (6). S—JLugo. SF—Sizemore, Lowell. GIDP—Blake, Pedroia, JDrew, JLugo.
Runners left in scoring position—Cleveland 3 (Sizemore, Garko, JhPeralta).
Runners moved up—DOrtiz.
DP—Cleveland 3 (JhPeralta, ACabrera and Garko), (JhPeralta, ACabrera and Garko), (ACabrera and Garko); Boston 1 (Lowell, Pedroia and Youkilis).
| Cleveland | IP | H | R | ER | BB | SO | NP | ERA |
| Westbrook L,1-1 | 6 | 9 | 3 | 3 | 1 | 5 | 93 | 3.55 |
| RBetancourt | 1 2/3 | 5 | 7 | 6 | 1 | 1 | 41 | 6.75 |
| Lewis | 1/3 | 1 | 1 | 1 | 0 | 1 | 9 | 6.35 |
| Boston | IP | H | R | ER | BB | SO | NP | ERA |
| Matsuzaka W,1-1 | 5 | 6 | 2 | 2 | 0 | 3 | 88 | 5.59 |
| Okajima H,1 | 2 | 3 | 0 | 0 | 0 | 0 | 25 | 0.00 |
| Papelbon S,1 | 2 | 1 | 0 | 0 | 0 | 1 | 16 | 0.00 |
Okajima pitched to 2 batters in the 8th.
Inherited runners-scored—Lewis 1-1, Papelbon 2-0.
IBB—off RBetancourt (Ellsbury) 1, off Westbrook (MRamirez) 1. WP—Matsuzaka.
T—3:33. A—37,165 (36,525).