Experts warn of spread of drug-resistant TB

BEIJING – The world is on the cusp of an explosion of drug-resistant tuberculosis cases that could deluge hospitals and leave physicians fighting a nearly untreatable malady with little help from modern drugs, global experts said Wednesday.

“The situation is already alarming, and poised to grow much worse very quickly,” said Dr. Margaret Chan, the director-general of the World Health Organization.

With Bill Gates at her side, Chan urged health officials from 27 countries at a three-day forum in Beijing on drug-resistant TB to recognize the warning signs of what looms ahead, saying that traditional drugs are useless against some strains of tuberculosis and health-care costs for treating those strains can be 100 to 200 times more than for regular tuberculosis.

“This is a situation set to spiral out of control. Call it what you may: a time bomb or a powder keg. Any way you look at it, this is a potentially explosive situation,” Chan warned.

Gates, the software magnate turned philanthropist, said scientific overconfidence had led to a lack of innovation and urgency in fighting tuberculosis, which affects 9 million people each year, killing nearly 2 million of them.

“The most commonly used diagnostic test is today more than 125 years old,” Gates said. “The vaccine was developed more than 80 years ago, and drugs have not changed in 50 years.”

Tuberculosis is a highly contagious bacterial infection that attacks the lungs and can affect other organs as well. Coughing, sneezing and even talking can spread the bacteria. If untreated, a person with TB can infect 10 to 15 other people in a year.