At Charlotte, N.C.
Zack Novak scored 14 points, including two 3-pointers in a decisive spurt to start the second half, and the Wolverines (21-13) beat the listless Volunteers (19-15).
The loss was the eighth in 12 games for the Volunteers, and coach Bruce Pearl’s future is in question after his athletic director recently said “the jury is still out” on whether Pearl will return.
In only its second NCAA tournament appearance since 1998, Michigan turned a four- point halftime lead into a rout.
Kyrie Irving scored 14 points in his first game in three months, and the Blue Devils (31-4) routed the Pirates (24-9) for coach Mike Krzyzewski’s 899th career victory.
The Blue Devils never trailed and shot 53 percent while dominating from the start, winning their fourth straight.
Hampton’s top three scorers – Darrion Pellum, Kwame Morgan and Charles Funches – were a combined 9 for 29 from the field.
At Charlotte, N.C.
(2) North Carolina102
(15) Long Island87
Tyler Zeller scored 32 points, John Henson added 28, the Tar Heels (27-7) used their hulking size to overcome sloppiness in a victory over the scrappy Blackbirds (27-6).
Harrison Barnes added 24 points and 16 rebounds for the Tar Heels, who eventually wore down the Blackbirds.
LIU faded after rallying to tie with under 5 minutes left in the first half as its nation-best 13-game winning streak was snapped.
Isaiah Thomas scored 19 points and the Huskies (24-10) held off a late rally to beat the Bulldogs (21-12).
Scott Suggs added 10 points for the Huskies, who shot 43 percent and withstood a frantic final-minute push to win their fifth straight NCAA tournament opener.
Trey Thompkins had 26 points and 11 rebounds for the Bulldogs, who trailed by 10 with 2 minutes left but made things interesting in the closing seconds.
(8) George Mason61
Luke Hancock hit a 3-pointer with 21 seconds left, capping the Patriots’ (27-6) comeback and keeping the one-time March darlings playing with a win over the Wildcats (21-12).
Villanova missed its last shot and Mike Morrison slammed home one final basket for George Mason.
This was the latest and last collapse for the Wildcats, who end the season on a six-game losing streak. They were once ranked as high as No. 5 but failed to get out of the first weekend of the NCAA tournament for the second straight year.
George Mason, which earned an at-large bid, won its first tournament game for the first time since its Final Four run in 2006.
(1) Ohio St.75
(16) Texas-San Antonio46
William Buford scored 18 points, freshman Jared Sullinger added 11, and the Buckeyes (33-2) looked the part of a No. 1 overall seed in rolling to a win over the Roadrunners (20-14).
Ohio State built a 16-point halftime lead, ballooned it to 38 in the second half and were never threatened by the Roadrunners.
Darius Johnson-Odum scored 19 points, Jimmy Butler had 15 and the Golden Eagles (21-14) squashed the Musketeers’ (24-8) bid for a fourth straight round of 16 appearance with a win.
Xavier and Michigan State were the only two programs to reach the round of 16 each of the last three tournaments.
Xavier’s Tu Holloway, the Atlantic 10 player of the year, missed his first seven field-goal attempts and scored only five points.
(14) Indiana State60
Defensive stopper Rick Jackson scored a season-high 23 points, C.J. Fair added 14 and the Orange (27-7) began taking care of “unfinished business” with a win over the Sycamores (20-14).
Syracuse wants to make up for last season’s disappointing tourney appearance, when its title run as a No. 1 seed ended with a loss to upstart Butler in the round of 16.