Jose Ramirez was 4 for 4 with a pair of three-run homers for Cleveland, and Detroit Tigers ace Justin Verlander matched a career high by allowing nine runs Saturday in a 13-6 loss to the Indians in Cleveland.
Ramirez had a career-high six RBIs with home runs in the first off Verlander (1-1) and in the eighth against Anibal Sanchez.
Verlander (1-1) gave up 11 hits in four-plus innings, including home runs by Carlos Santana and Lonnie Chisenhall. Santana had three of Cleveland’s 19 hits and four RBIs.
Corey Kluber (1-1) struck out eight in 6 1/3 innings, allowing six runs and eight hits.
Mariners 5, Rangers 0: James Paxton extended his season-opening scoreless streak to 21 innings, Taylor Motter hit a three-run homer and Seattle beat visiting Texas.
Paxton (2-0) threw eight innings of two-hit ball, walking one and striking out nine. He hasn’t allowed a run yet in three starts this year, and his scoreless stretch is a team record to open a season. He’s the 10th pitcher in the majors ever to start a year with three scoreless starts of at least six innings.
Andrew Cashner (0-1) lost in his first start since signing with Texas as a free agent.
Twins 6, White Sox 0: Ervin Santana (3-0) pitched a one-hitter for the first complete-game victory by a pitcher in the major leagues this season, stopping visiting Chicago’s three-game winning streak.
Santana’s (3-0) struck out eight, walked one and retired his final 18 batters. Chicago had just two runners: Omar Narvaez singled with one out in the third and Avisail Garcia walked leading off the fourth.
Jose Quintana (0-3) gave up hits to six of his first seven batters in a 39-pitch first inning, including Max Kepler’s two-run triple.
Rockies 5, Giants 0: Tyler Chatwood (1-2) pitched 5 2/3 perfect innings before Chris Marrero’s single and finished with a two-hitter for his first big league shutout as Colorado defeated the Giants in San Francisco.
Nolan Arenado had three hits, including a home run off Matt Moore (1-2), who allowed five runs, 10 hits and three walks in 5 2/3 innings.
Dodgers 8, Diamondbacks 4: Yasiel Puig hit a three-run homer in the eighth inning and Los Angeles overcame a sloppy defensive game to beat visiting Arizona.
Alex Wood (1-0) pitched 3 1/3 scoreless innings of relief to earn the win and Kenley Jansen got the last four outs for his third save.
Diamondbacks starter Patrick Corbin (1-2) struggled in his six innings, giving up five runs – three earned – and nine hits with three walks.
Yankees 3, Cardinals 2: St. Louis ace Carlos Martinez (0-2) put on a drastically uneven performance, walking a career-high eight while striking out 11 in 5 1/3 innings as St. Louis lost to the Yankees at New York. Martinez was the first pitcher since Randy Johnson in 1993 with at least eight walks and 11 strikeouts in a game.
The Yankees won their sixth straight despite tying a team record by fanning 17 times. They got plenty of help from sloppy St. Louis, which at 3-8 is off to its worst start in 20 years and has the poorest record in the N.L.
CC Sabathia (2-0) took a shutout into the eighth. Jedd Gyorko and Stephen Piscotty homered late for St. Louis. Tyler Clippard got his first save, striking out Randal Grichuk with two on.
Blue Jays 2, Orioles 1: Kendrys Morales homered off Tyler Wilson (1-1) leading off the bottom of the ninth, and Toronto (2-9) stopped a seven-game losing streak with the win over visiting Baltimore.
Roberto Osuna (1-0) had allowed Jonathan Schoop’s sacrifice fly in the top half.
Reds 7, Brewers 5: Jesse Winker doubled home the go-ahead run in the sixth off Carlos Torres (0-1) with his first major league hit, and Cincinnati overcame two homers by Eric Thames and stopped visiting Milwaukee’s four-game winning streak.
Reds left-hander Brandon Finnegan came out of the game after the first inning because of a strained muscle in the back of his left side. The Reds already have three starters on the disabled list.
Raisel Iglesias (1-0) allowed one run in two innings as manager Bryan Price used five relievers after Finnegan’s early departure. Michael Lorenzen walked a batter in the ninth while getting his first career save.
Pirates 8, Cubs 7: Andrew McCutchen hit a go-ahead, three-run homer of Pedro Strop (0-1) in a five-run seventh as Pittsburgh won at Chicago. Pittsburgh has won two straight against the Cubs after going 4-14 against Chicago last season, including 1-8 at Wrigley Field.
Francisco Cervelli and Starling Marte also homered for Pittsburgh on a hot, windy afternoon. Chicago led 6-2 before Marte’s solo drive in the sixth inning off starter Jake Arrieta.
Trevor Williams (1-0) pitched a one-hit seventh.
Red Sox 2, Rays 1: Chris Sale (1-1) struck out 12 over seven innings for his first victory with Boston, allowing one run and three hits as the Red Sox defeated Tampa Bay at Boston.
Sandy Leon’s broken-bat, bases-loaded ground out pushed across the tiebreaking run in the seventh. The Red Sox loaded the bases on two singles and a walk against Tommy Hunter (0-1).
Mitch Moreland homered for Boston.
Astros 10, Athletics 6: George Springer hit a two-run homer in the eighth as visiting Houston rallied from a 5-0 deficit to defeat Oakland.
Sean Manaea and Ryan Dull combined to pitch six hitless innings for Oakland.
Carlos Correa left after being hit by a pitch on his right hand in the ninth, and Astros said an X-ray was negative.
Will Harris (1-0) struck out two in a scoreless seventh, and Santiago Casilla (0-1) was the loser.
Phillies 4, Nationals 2: Cesar Hernandez hit a tiebreaking, two-run homer off Joe Blanton in the eighth inning and Philadelphia went on to defeat the Nationals at Washington.
Jeremy Hellickson (2-0) allowed two runs and four hits in seven innings. Hector Neris pitched a perfect eighth, and Joaquin Benoit a 1-2-3 ninth for his first save since signing with the Phillies as a free agent during the offseason.
Marlins 5, Mets 4: Christian Yelich and Giancarlo Stanton hit back-to-back homers against Fernando Salas (0-1) to cap a three-run eighth as Miami rallied from a 4-2 deficit to defeat visiting New York.
Justin Bour and Marcell Ozuna hit consecutive homers for Miami in the second off Jacob deGrom, who tied a career high with 13 strikeouts in seven innings.
Asdrubal Cabrera hit a solo homer in the eighth against Junichi Tazawa (1-0) to put the Mets ahead 4-2. A.J. Ramos pitched a perfect ninth for his second save.
Braves 4, Padres 2: Winless at Turner Field, R.A. Dickey got a victory in his first appearance SunTrust Park. Atlanta has won three straight following a five-game losing streak, including the first two games at its new ballpark.
Dickey (1-1) gave up two runs and seven hits in six-plus innings with six strikeouts, allowing consecutive home runs in the second to Hunter Renfroe and Austin Hedges. The 42-year-old knuckleballer was pitching in his third Atlanta ballpark. He got two victories for the U.S. team that won the 1996 Olympic bronze medal at Atlanta Fulton-County Stadium but was 0-3 against the Braves at Turner Field in six starts and three relief appearances.
Brandon Phillips and Adonis Garcia homered in the sixth off Clayton Richard (1-2).
Royals 3, Angels 2: Mike Moustakas’ fifth home run this season, a drive off off Jose Alvarez (0-1), broke an eighth-inning tie and Kansas City defeated Los Angeles at Kansas City, Missouri.
Ben Revere had knotted the score in the seventh with a two-out RBI single against Joakim Soria (1-0).
Kelvin Herrera pitched a perfect ninth for his second save.
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