Dustin Keller will miss the entire season with a knee injury that leaves the Miami Dolphins without much experience at tight end, a position in which they were counting on an upgrade to enliven their offense in 2013.

Keller seriously injured his right knee during Saturday’s preseason game at Houston, two people familiar with the diagnosis said Sunday. They confirmed the extent of the injury on condition of anonymity because the Dolphins made no public comment.

Keller signed a $4.25 million, one-year contract with the Dolphins in March after five seasons with the Jets.

Miami ranked 30th in the NFL last year with 13 touchdown passes, but Tannehill and Keller had clicked in training camp and connected on a 22-yard touchdown pass in the second exhibition game.

Around the league

Buffalo QB EJ Manuel had what Bills coach Doug Marrone would only call “a procedure” on his left knee and will miss the rest of the preseason. Marrone says that Manuel has a good chance of returning before the start of the regular season. … Broncos DE Derek Wolfe says he’ll be back on the field soon. Wolfe was sent to a hospital for evaluation of a possible cervical spine injury after he lay prone on the field for a few minutes following a hit to his head in Seattle on Saturday night.