Gamebreakers
Rushing
| Player, team | Att. | Yds. | TD |
| DeAngelo Williams, Memphis | 33 | 262 | 4 |
| Walter Reyes, Syracuse | 19 | 237 | 2 |
| Ryan Moats, Louisiana Tech | 34 | 233 | 4 |
| Anthony Davis, Wisconsin | 27 | 213 | 3 |
| Marcus Rucker, Rice | 23 | 201 | 2 |
Passing
| Player, team | A-C. | Yds. | TD |
| Bruce Gradkowski, Toledo | 26-34 | 455 | 6 |
| Brady Quinn, Notre Dame | 26-46 | 432 | 1 |
| Kyle Orton, Purdue | 21-31 | 385 | 4 |
| Sonny Cumbie, Texas Tech | 36-55 | 369 | 0 |
| Omar Jacobs, Bowling Green | 21-26 | 367 | 4 |
Receiving
| Player, team | No. | Yds. | TD |
| Kenny Higgins, Toledo | 10 | 233 | 3 |
| David Anderson, Colorado St. | 12 | 232 | 1 |
| Taylor Stubblefield, Purdue | 7 | 181 | 2 |
| Chase Lyman, California | 5 | 176 | 3 |
| Braylon Edwards, Michigan | 8 | 165 | 2 |
Heisman watch
Kyle Orton, Purdue: Had four TD passes as Purdue won at Notre Dame for first time since ‘74.
Cedric Benson, Texas: Rushed for 188 yards and three TDs in a win over Baylor.
Vernand Morency, Oklahoma State: Ran for 143 yards and two TDs in a victory over Iowa State.