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The Spokesman-Review Newspaper
Spokane, Washington  Est. May 19, 1883

Generic Wellbutrin troubles some

Joe Graedon and Teresa Graedon The Spokesman-Review

Q. I have taken Wellbutrin XL for two years, and it has taken care of my depression beautifully. In January, my insurance company switched me to the generic called Budeprion XL. I didn’t think twice about it. I just assumed it was as good as Wellbutrin XL.

After a few months of thinking I was losing my mind and that Wellbutrin just wasn’t working anymore, it finally dawned on me that I was no longer taking WELLBUTRIN! (I honestly hadn’t even thought about the generic.)

I have been very depressed, crying and irritable, with no energy or ambition. While I am not suicidal, it sure doesn’t sound like a bad plan most days. I will stop Budeprion XL immediately, even though I will have to pay full price for Wellbutrin XL.

A. More than a dozen people have contacted us about experiences that are strikingly similar to yours. Some of them reported nausea or dizziness as side effects of Budeprion XL; all of them said their symptoms of depression had returned.

We have no scientific evidence that there is a difference between the brand name and the generic. Nevertheless, so many reports convince us that there should be an investigation.

We have arranged with the Food and Drug Administration to analyze any generic pills that readers of The People’s Pharmacy suspect are not equivalent to their branded counterparts. Please describe your experience and send your generic pills with as much information as possible: Name of medication, name of generic drug maker, lot number and date dispensed. (Data may be available from the pharmacy.) Send the parcel to: Graedons’ People’s Pharmacy, P.O. Box 52027, Durham, NC 27717-2027.

Q. I try to limit my family’s salt intake because high blood pressure runs in my husband’s family. I found Morton Lite Salt at the store. The package claims it has “half the sodium of table salt … can be used in all your recipes just like regular salt with the same great results. It cooks the same, bakes the same …” All of that sounds perfect.

But it also says “For normal healthy people. Not to be used by persons on sodium or potassium restricted diets unless approved by a physician.”

I’m a little confused. If we only use this when we would’ve used salt anyway, is it safe for my family? What if I’m making something for guests and I don’t know the medical status of everyone who might consume some?

A. You have found a reasonable way to cut back on sodium when cooking for your family without giving up the taste of salt entirely. Guests who must restrict their intake of sodium more completely should be polite enough to tell you that before they arrive for dinner.

Q. I have been taking Ambien for about six months. It really helps me get a decent night’s sleep, but now I have heartburn.

Can Ambien cause reflux? I hate to take Nexium to counteract indigestion that might be caused by Ambien.

A. Ambien (zolpidem) can cause indigestion or reflux. Here is another reader’s experience: “Ambien gave me a great night’s sleep after years of wakefulness. The cost was disabling digestive problems: bloating, pain and acid reflux.

“After a year of pain, more than $20,000 in uncomfortable testing and drugs for reflux, I took myself off Ambien. Two doctors had insisted that my digestive woes were not related to Ambien, but after three nights of sleeplessness, the digestive problems went away.”