Gamebreakers
Rushing
| Player, team | Att. | Yds. | TD |
| Garrett Wolfe, Northern Illinois | 43 | 325 | 2 |
| Alley Broussard, LSU | 26 | 250 | 3 |
| Adrian Peterson, Oklahoma | 32 | 240 | 3 |
| Uril Parrish, Tulsa | 30 | 229 | 2 |
| DeAngelo Williams, Memphis | 32 | 225 | 4 |
Passing
| Player, team | C-A | Yds. | TD |
| Kyle Orton, Purdue | 33-54 | 518 | 6 |
| Charlie Frye, Akron | 26-43 | 436 | 3 |
| Joey Lynch, Ball State | 22-34 | 397 | 4 |
| Gino Guidugli, Cincinnati | 30-36 | 377 | 3 |
| Kevin Kolb, Houston | 30-44 | 370 | 2 |
Receiving
| Player, team | No. | Yds. | TD |
| Dante Ridgeway, Ball State | 10 | 215 | 1 |
| Kyle Ingraham, Purdue | 11 | 206 | 2 |
| Braylon Edwards, Michigan | 11 | 172 | 1 |
| Hannibal Thomas, Cincinnati | 10 | 162 | 0 |
| Brandon Smith, Vanderbilt | 8 | 160 | 1 |
Heisman watch
Jason White, Oklahoma: Has passed for 2,707 yards and 30 TDs with four interceptions.
Adrian Peterson, Oklahoma: Ran for 240 yards and 3 TDs against Baylor. Has 10 100-yard games.
Alex Smith, Utah: Suffered through worst outing against BYU, tossing 2 picks to double season total.